In Vivo Tracking of Human Hematopoiesis Reveals Patterns of Clonal Dynamics during Early and Steady-State Reconstitution Phases

Hematopoietic stem/progenitor cells (HSPCs) are capable of supporting the lifelong production of blood cells exerting a wide spectrum of functions. Lentiviral vector HSPC gene therapy generates a human hematopoietic system stably marked at the clonal level by vector integration sites (ISs). Using IS...

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Bibliografske podrobnosti
izdano v:Cell Stem Cell
Main Authors: Biasco, Luca, Pellin, Danilo, Scala, Serena, Dionisio, Francesca, Basso-Ricci, Luca, Leonardelli, Lorena, Scaramuzza, Samantha, Baricordi, Cristina, Ferrua, Francesca, Cicalese, Maria Pia, Giannelli, Stefania, Neduva, Victor, Dow, David J., Schmidt, Manfred, Von Kalle, Christof, Roncarolo, Maria Grazia, Ciceri, Fabio, Vicard, Paola, Wit, Ernst, Di Serio, Clelia, Naldini, Luigi, Aiuti, Alessandro
Format: Artigo
Jezik:Inglês
Izdano: Cell Press 2016
Teme:
Short Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4942697/
https://ncbi.nlm.nih.gov/pubmed/27237736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2016.04.016
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