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CFH Y402H polymorphism and the complement activation product C5a: effects on NF-κB activation and inflammasome gene regulation
BACKGROUND/AIMS: The Y402H polymorphism in the complement factor H (CFH) gene is an important risk factor for age-related macular degeneration (AMD). Complement activation products and proinflammatory cytokines are associated with this polymorphism at the systemic level, but less is known of the ass...
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| Publicado no: | Br J Ophthalmol |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4942273/ https://ncbi.nlm.nih.gov/pubmed/26746578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bjophthalmol-2015-307213 |
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