Role of adenylyl cyclase in reduced β-adrenoceptor-mediated vasorelaxation during maturation

Beta-adrenergic receptor (βAR)-dependent blood vessel relaxation is impaired in older animals and G protein activation has been suggested as the causative mechanism. Here, we investigated the role of βAR subtypes (β1AR, β2AR, and β3AR) and cAMP in maturation-dependent vasorelaxation impairment. Aort...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Braz J Med Biol Res
Autori principali: López-Canales, O.A., Castillo-Hernandez, M.C., Vargas-Robles, H., Rios, A., López-Canales, J.S., Escalante, B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Associação Brasileira de Divulgação Científica 2016
Soggetti:
Biomedical Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4942227/
https://ncbi.nlm.nih.gov/pubmed/27383122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/1414-431X20165285
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