The role of adenylyl cyclase isoform 6 in β-adrenoceptor signalling in murine airways

BACKGROUND AND PURPOSE: Adenylyl cyclase (AC) is a key signalling enzyme for many GPCRs and catalyses the conversion of ATP to cAMP which, in turn, is a crucial determinant of many biological responses. β-Adrenoceptor agonists are prescribed as bronchodilators for asthma and chronic obstructive pulm...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Birrell, Mark A, Bonvini, Sara J, Wortley, Michael A, Buckley, James, Yew-Booth, Liang, Maher, Sarah A, Dale, Nicole, Dubuis, Eric D, Belvisi, Maria G
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2015
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4280973/
https://ncbi.nlm.nih.gov/pubmed/25205328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12905
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