Effect of BET Missense Mutations on Bromodomain Function, Inhibitor Binding and Stability

Lysine acetylation is an important epigenetic mark regulating gene transcription and chromatin structure. Acetylated lysine residues are specifically recognized by bromodomains, small protein interaction modules that read these modification in a sequence and acetylation dependent way regulating the...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Lori, Laura, Pasquo, Alessandra, Lori, Clorinda, Petrosino, Maria, Chiaraluce, Roberta, Tallant, Cynthia, Knapp, Stefan, Consalvi, Valerio
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2016
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4942050/
https://ncbi.nlm.nih.gov/pubmed/27403962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159180
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