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In-vivo imaging of dendritic pruning in dentate granule cells

We longitudinally imaged the developing dendrites of adult-born mouse dentate granule cells (DGCs) in vivo and found that they underwent over-branching and pruning. Exposure to an enriched environment (EE) and constraining dendritic growth by disrupting Wnt signaling led to increased branch addition...

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Detalles Bibliográficos
Publicado en:Nat Neurosci
Main Authors: Gonçalves, J. Tiago, Bloyd, Cooper W., Shtrahman, Matthew, Johnston, Stephen T., Schafer, Simon T., Parylak, Sarah L., Tran, Thanh, Chang, Tina, Gage, Fred H.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941946/
https://ncbi.nlm.nih.gov/pubmed/27135217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.4301
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