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An in vivo model of functional and vascularized human brain organoids

Differentiation of human pluripotent stem cells to small brain-like structures known as brain organoids offers an unprecedented opportunity to model human brain development and disease. To provide a vascularized and functional in vivo model of brain organoids, we established a method for transplanti...

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Bibliografische gegevens
Gepubliceerd in:Nat Biotechnol
Hoofdauteurs: Mansour, Abed AlFatah, Gonçalves, J Tiago, Bloyd, Cooper W, Li, Hao, Fernandes, Sarah, Quang, Daphne, Johnston, Stephen, Parylak, Sarah L, Jin, Xin, Gage, Fred H
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6331203/
https://ncbi.nlm.nih.gov/pubmed/29658944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.4127
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