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Dynamic heterogeneity as a strategy of stem cell self-renewal

To maintain cycling adult tissue in homeostasis the balance between proliferation and differentiation of stem cells needs to be precisely regulated. To investigate how stem cells achieve perfect self-renewal, emphasis has been placed on models in which stem cells progress sequentially through a one-...

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Bibliographische Detailangaben
Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Greulich, Philip, Simons, Benjamin D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941513/
https://ncbi.nlm.nih.gov/pubmed/27313213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1602779113
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