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Self-renewal of embryonic stem cells by a small molecule
A cell-based screen of chemical libraries was carried out to identify small molecules that control the self-renewal of ES cells. A previously uncharacterized heterocycle, SC1, was discovered that allows one to propagate murine ES cells in an undifferentiated, pluripotent state under chemically defin...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2006
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1859921/ https://ncbi.nlm.nih.gov/pubmed/17088537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0608156103 |
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