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Self-renewal of embryonic stem cells by a small molecule

A cell-based screen of chemical libraries was carried out to identify small molecules that control the self-renewal of ES cells. A previously uncharacterized heterocycle, SC1, was discovered that allows one to propagate murine ES cells in an undifferentiated, pluripotent state under chemically defin...

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Detalhes bibliográficos
Main Authors: Chen, Shuibing, Do, Jeong Tae, Zhang, Qisheng, Yao, Shuyuan, Yan, Feng, Peters, Eric C., Schöler, Hans R., Schultz, Peter G., Ding, Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1859921/
https://ncbi.nlm.nih.gov/pubmed/17088537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0608156103
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