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Cell type-specific control of protein synthesis and proliferation by FGF-dependent signaling to the translation repressor 4E-BP

Regulation of protein synthesis plays a vital role in posttranscriptional modulation of gene expression. Translational control most commonly targets the initiation of protein synthesis: loading 40S ribosome complexes onto mRNA and AUG start codon recognition. This step is initiated by eukaryotic ini...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Ruoff, Rachel, Katsara, Olga, Kolupaeva, Victoria
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941506/
https://ncbi.nlm.nih.gov/pubmed/27313212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1605451113
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