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Structures of the orthosomycin antibiotics avilamycin and evernimicin in complex with the bacterial 70S ribosome
The ribosome is one of the major targets for therapeutic antibiotics; however, the rise in multidrug resistance is a growing threat to the utility of our current arsenal. The orthosomycin antibiotics evernimicin (EVN) and avilamycin (AVI) target the ribosome and do not display cross-resistance with...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4941455/ https://ncbi.nlm.nih.gov/pubmed/27330110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1604790113 |
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