Chronic inflammation contributes to the development of hepatocellular carcinoma by decreasing miR-122 levels

Persistent inflammation in chronic hepatitis plays a major role in the development of hepatocellular carcinoma (HCC). In this study, the major inflammatory cytokines expressed in chronic hepatitis, IL-6 and TNF-α, induced a marked decrease in microRNA-122 (miR-122) levels, and miR-122 expression was...

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Vydáno v:Oncotarget
Hlavní autoři: Li, Changfei, Deng, Mengmeng, Hu, Jun, Li, Xin, Chen, Lizhao, Ju, Ying, Hao, Junli, Meng, Songdong
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941368/
https://ncbi.nlm.nih.gov/pubmed/26933995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7740
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