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MicroRNA-199a and -214 as potential therapeutic targets in pancreatic stellate cells in pancreatic tumor
Pancreatic stellate cells (PSCs) are the key precursor cells for cancer-associated fibroblasts (CAFs) in pancreatic tumor stroma. In this study, we explored miRNA as therapeutic targets in tumor stroma and found miR-199a-3p and miR-214-3p induced in patient-derived pancreatic CAFs and TGF-β-activate...
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| Publicado en: | Oncotarget |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Impact Journals LLC
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4941323/ https://ncbi.nlm.nih.gov/pubmed/26918939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7651 |
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