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Epigallocatechin-3-gallate targets cancer stem-like cells and enhances 5-fluorouracil chemosensitivity in colorectal cancer

Resistance to cytotoxic chemotherapy is a major cause of mortality in colorectal cancer (CRC) patients. A small subset of cancer cells, termed “cancer stem cells” (CSCs), are believed to be key contributors of chemoresistance and tumor recurrence. Recently, epigallocatechin-3-gallate (EGCG), an acti...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Toden, Shusuke, Tran, Hanh-My, Tovar-Camargo, Oscar A., Okugawa, Yoshinaga, Goel, Ajay
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941304/
https://ncbi.nlm.nih.gov/pubmed/26930714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7567
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