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Genetic association study identifies a functional CNV in the WWOX gene contributes to the risk of intracranial aneurysms

Intracranial aneurysms (IAs) accounts for 85% of hemorrhagic stroke. Genetic factors have been known to play an important role in the development of IAs. A functional CNV (CNV-67048) of human WW domain-containing oxidoreductase (WWOX), which has been identified as a tumor suppressor gene in multiple...

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Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Fan, Jin, Sun, Wen, Lin, Min, Yu, Ke, Wang, Jian, Duan, Dan, Zheng, Bo, Yang, Zhenghui, Wang, Qingsong
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941300/
https://ncbi.nlm.nih.gov/pubmed/26910372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7546
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