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Integrated experimental and simulation study of the response to sequential treatment with erlotinib and gemcitabine in pancreatic cancer

The combination of erlotinib with gemcitabine is one of the most promising therapies for advanced pancreatic cancer. Aiming at optimizing this combination, we analyzed in detail the response to sequential treatments with erlotinib → gemcitabine and gemcitabine → erlotinib with an 18 h interval, adop...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Ubezio, Paolo, Falcetta, Francesca, Carrassa, Laura, Lupi, Monica
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941256/
https://ncbi.nlm.nih.gov/pubmed/26909860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7491
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