CCR5 knockout suppresses experimental autoimmune encephalomyelitis in C57BL/6 mice

Multiple sclerosis (MS) is an inflammatory disease in which myelin in the spinal cord is damaged. C-C chemokine receptor type 5 (CCR5) is implicated in immune cell migration and cytokine release in central nervous system (CNS). We investigated whether CCR5 plays a role in MS progression using a muri...

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Vydáno v:Oncotarget
Hlavní autoři: Gu, Sun Mi, Park, Mi Hee, Yun, Hyung Mun, Han, Sang Bae, Oh, Ki Wan, Son, Dong Ju, Yun, Jae Suk, Hong, Jin Tae
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper: Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941248/
https://ncbi.nlm.nih.gov/pubmed/26985768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8097
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