The histone deacetylase inhibitor trichostatin A suppresses murine innate allergic inflammation by blocking group 2 innate lymphoid cell (ILC2) activation

BACKGROUND: Group 2 innate lymphoid cells (ILC2) are an important source of the type 2 cytokines interleukin (IL)-5 and IL-13 that are critical to the allergic airway phenotype. Previous studies reported that histone deacetylase (HDAC) inhibition by trichostatin A (TSA) downregulated adaptive allerg...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Thorax
Hlavní autoři: Toki, Shinji, Goleniewska, Kasia, Reiss, Sara, Zhou, Weisong, Newcomb, Dawn C, Bloodworth, Melissa H, Stier, Matthew T, Boyd, Kelli L, Polosukhin, Vasiliy V, Subramaniam, Sriram, Peebles, R Stokes
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Publishing Group 2016
Témata:
Respiratory Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941189/
https://ncbi.nlm.nih.gov/pubmed/27071418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thoraxjnl-2015-207728
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky