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Induced pluripotent stem cells in Parkinson's disease: scientific and clinical challenges

Induced pluripotent stem cells (iPSCs), which greatly circumvent the ethical issue of human embryonic stem cells (ESCs), can be induced to differentiate to dopaminergic (DA) neurons, and hence be used as a human disease model for Parkinson's disease (PD). iPSCs can be also utilised to probe the...

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Bibliographische Detailangaben
Veröffentlicht in:J Neurol Neurosurg Psychiatry
Hauptverfasser: Xiao, Bin, Ng, Huck Hui, Takahashi, Ryosuke, Tan, Eng-King
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941130/
https://ncbi.nlm.nih.gov/pubmed/26833176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp-2015-312036
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