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Induced pluripotent stem cells in Parkinson's disease: scientific and clinical challenges

Induced pluripotent stem cells (iPSCs), which greatly circumvent the ethical issue of human embryonic stem cells (ESCs), can be induced to differentiate to dopaminergic (DA) neurons, and hence be used as a human disease model for Parkinson's disease (PD). iPSCs can be also utilised to probe the...

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Detalhes bibliográficos
Publicado no:J Neurol Neurosurg Psychiatry
Main Authors: Xiao, Bin, Ng, Huck Hui, Takahashi, Ryosuke, Tan, Eng-King
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941130/
https://ncbi.nlm.nih.gov/pubmed/26833176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp-2015-312036
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