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Early-life stress leads to impaired spatial learning and memory in middle-aged ApoE4-TR mice
BACKGROUND: Apolipoprotein E (ApoE) is a major lipid carrier that supports lipid transport and injury repair in the brain. The APOE ε4 allele is associated with depression, mild cognitive impairment (MCI) and dementia; however, the precise molecular mechanism through which ApoE4 influences the risk...
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Publicado no: | Mol Neurodegener |
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Main Authors: | , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4941053/ https://ncbi.nlm.nih.gov/pubmed/27406263 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-016-0107-2 |
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