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Early-life stress leads to impaired spatial learning and memory in middle-aged ApoE4-TR mice

BACKGROUND: Apolipoprotein E (ApoE) is a major lipid carrier that supports lipid transport and injury repair in the brain. The APOE ε4 allele is associated with depression, mild cognitive impairment (MCI) and dementia; however, the precise molecular mechanism through which ApoE4 influences the risk...

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Detalhes bibliográficos
Publicado no:Mol Neurodegener
Main Authors: Lin, Lan-yan, Zhang, Jing, Dai, Xiao-man, Xiao, Nai-an, Wu, Xi-lin, Wei, Zhen, Fang, Wen-ting, Zhu, Yuan-gui, Chen, Xiao-chun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941053/
https://ncbi.nlm.nih.gov/pubmed/27406263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-016-0107-2
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