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Impairments in spatial memory retention of GFAP-apoE4 female mice

The human apolipoprotein E isoforms, apoE2, apoE3, and apoE4, have differential effects on brain function. Compared to apoE3, apoE4 increases the risk of age-related cognitive decline in humans and female mice expressing apoE in neurons. Here we show impaired spatial memory retention in female mice...

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Detalhes bibliográficos
Main Authors: van Meer, Peter, Acevedo, Summer, Raber, Jacob
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950679/
https://ncbi.nlm.nih.gov/pubmed/17126420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2006.10.024
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