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Calcitonin gene-related peptide contributes to peripheral nerve injury-induced mechanical hypersensitivity through CCL5 and p38 pathways
The role of calcitonin gene related peptide (CGRP) in neuropathic pain was investigated in a mouse model of neuropathic pain, spinal nerve L5 transection (L5Tx). Intrathecal injection (i.t) of CGRP(8–37,) a CGRP antagonist, significantly reduced L5Tx-induced mechanical hypersensitivity and lumbar sp...
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| Izdano u: | J Neuroimmunol |
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| Glavni autori: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4940993/ https://ncbi.nlm.nih.gov/pubmed/27397078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2016.05.003 |
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