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Efficient production of pronuclear embryos in breeding and nonbreeding season for generating transgenic sheep overexpressing TLR4

BACKGROUND: Brucella is a zoonotic Gram-negative pathogen that causes abortion and infertility in ruminants and humans. TLR4 is the receptor for LPS which can recognize Brucella and initiate antigen-presenting cell activities that affect both innate and adaptive immunity. Consequently, transgenic sh...

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Bibliographic Details
Published in:J Anim Sci Biotechnol
Main Authors: Li, Yan, Lian, Di, Deng, Shoulong, Zhang, Xiaosheng, Zhang, Jinlong, Li, Wenting, Bai, Hai, Wang, Zhixian, Wu, Hongping, Fu, Juncai, Han, Hongbing, Feng, Jianzhong, Liu, Guoshi, Lian, Ling, Lian, Zhengxing
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4940989/
https://ncbi.nlm.nih.gov/pubmed/27408716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40104-016-0096-6
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