Toll-Like Receptor 4 Promotes NO Synthesis by Upregulating GCHI Expression under Oxidative Stress Conditions in Sheep Monocytes/Macrophages

Many groups of Gram-negative bacteria cause diseases that are harmful to sheep. Toll-like receptor 4 (TLR4), which is critical for detecting Gram-negative bacteria by the innate immune system, is activated by lipopolysaccharide (LPS) to initiate inflammatory responses and oxidative stress. Oxidation...

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Bibliographic Details
Published in:Oxid Med Cell Longev
Main Authors: Deng, Shoulong, Yu, Kun, Zhang, Baolu, Yao, Yuchang, Wang, Zhixian, Zhang, Jinlong, Zhang, Xiaosheng, Liu, Guoshi, Li, Ning, Liu, Yixun, Lian, Zhengxing
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2015
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4630417/
https://ncbi.nlm.nih.gov/pubmed/26576220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/359315
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