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The safety and efficacy of osimertinib for the treatment of EGFR T790M mutation positive non-small-cell lung cancer

First- and second-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are the evidence-based first-line treatment for metastatic non-small-cell lung cancers (NSCLCs) that harbor sensitizing EGFR mutations (i.e., exon 19 deletions or L858R). However, acquired resistan...

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Publicat a:Expert Rev Anticancer Ther
Autors principals: Gao, Xin, Le, Xiuning, Costa, Daniel B.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4940973/
https://ncbi.nlm.nih.gov/pubmed/26943236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/14737140.2016.1162103
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