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What Mutagenesis Can and Cannot Reveal About Allostery

Allosteric regulation of protein function is recognized to be widespread throughout biology; however, knowledge of allosteric mechanisms, the molecular changes within a protein that couple one binding site to another, is limited. Although mutagenesis is often used to probe allosteric mechanisms, we...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Carlson, Gerald M., Fenton, Aron W.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4940924/
https://ncbi.nlm.nih.gov/pubmed/27166800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.03.021
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