Polymorphisms in the Mannose-Binding Lectin Gene are Associated with Defective Mannose-Binding Lectin Functional Activity in Crohn’s Disease Patients

Mannose-binding lectin, together with mannose-associated serine proteases, activates the lectin pathway of the complement system and subsequent inflammatory mechanisms. An association between mannose-binding lectin deficiency and anti-Saccharomyces cerevisiae antibody levels is observed in Crohn’s d...

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Udgivet i:Sci Rep
Main Authors: Choteau, Laura, Vasseur, Francis, Lepretre, Frederic, Figeac, Martin, Gower-Rousseau, Corine, Dubuquoy, Laurent, Poulain, Daniel, Colombel, Jean-Frederic, Sendid, Boualem, Jawhara, Samir
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4940739/
https://ncbi.nlm.nih.gov/pubmed/27404661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29636
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