Novel Chemical Ligands to Ebola Virus and Marburg Virus Nucleoproteins Identified by Combining Affinity Mass Spectrometry and Metabolomics Approaches

The nucleoprotein (NP) of Ebola virus (EBOV) and Marburg virus (MARV) is an essential component of the viral ribonucleoprotein complex and significantly impacts replication and transcription of the viral RNA genome. Although NP is regarded as a promising antiviral druggable target, no chemical ligan...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Fu, Xu, Wang, Zhihua, Li, Lixin, Dong, Shishang, Li, Zhucui, Jiang, Zhenzuo, Wang, Yuefei, Shui, Wenqing
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2016
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4940736/
https://ncbi.nlm.nih.gov/pubmed/27403722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29680
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