Specific binding of the diphtheria tox regulatory element DtxR to the tox operator requires divalent heavy metal ions and a 9-base-pair interrupted palindromic sequence.

Eitemau Tebyg

• Molecular cloning and DNA sequence analysis of a diphtheria tox iron-dependent regulatory element (dtxR) from Corynebacterium diphtheriae.
  gan: Boyd, J, et al.
  Cyhoeddwyd: (1990)
• Mechanism of metal ion activation of the diphtheria toxin repressor DtxR
  gan: D'Aquino, J. Alejandro, et al.
  Cyhoeddwyd: (2005)
• Heterogeneity of diphtheria toxin gene, tox, and its regulatory element, dtxR, in Corynebacterium diphtheriae strains causing epidemic diphtheria in Russia and Ukraine.
  gan: Nakao, H, et al.
  Cyhoeddwyd: (1996)
• Cysteine-102 is positioned in the metal binding activation site of the Corynebacterium diphtheriae regulatory element DtxR.
  gan: Tao, X, et al.
  Cyhoeddwyd: (1993)
• Characterization of a defective diphtheria toxin repressor (dtxR) allele and analysis of dtxR transcription in wild-type and mutant strains of Corynebacterium diphtheriae.
  gan: Schmitt, M P, et al.
  Cyhoeddwyd: (1991)