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Mechanism of metal ion activation of the diphtheria toxin repressor DtxR

The diphtheria toxin repressor (DtxR) is a metal ion-activated transcriptional regulator that has been linked to the virulence of Corynebacterium diphtheriae. Structure determination has shown that there are two metal ion binding sites per repressor monomer, and site-directed mutagenesis has demonst...

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Detalhes bibliográficos
Main Authors: D'Aquino, J. Alejandro, Tetenbaum-Novatt, Jaclyn, White, Andre, Berkovitch, Fred, Ringe, Dagmar
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1317899/
https://ncbi.nlm.nih.gov/pubmed/16352732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500908102
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