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Disruption of Vitamin D and Calcium Signaling in Keratinocytes Predisposes to Skin Cancer
1,25 dihydroxyvitamin D (1,25(OH)(2)D), the active metabolite of vitamin D, and calcium regulate epidermal differentiation. 1,25(OH)(2)D exerts its effects through the vitamin D receptor (VDR), a transcription factor in the nuclear hormone receptor family, whereas calcium acts through the calcium se...
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| Publié dans: | Front Physiol |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4940389/ https://ncbi.nlm.nih.gov/pubmed/27462278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2016.00296 |
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