Disruption of Vitamin D and Calcium Signaling in Keratinocytes Predisposes to Skin Cancer

1,25 dihydroxyvitamin D (1,25(OH)(2)D), the active metabolite of vitamin D, and calcium regulate epidermal differentiation. 1,25(OH)(2)D exerts its effects through the vitamin D receptor (VDR), a transcription factor in the nuclear hormone receptor family, whereas calcium acts through the calcium se...

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Dades bibliogràfiques
Publicat a:Front Physiol
Autors principals: Bikle, Daniel D., Jiang, Yan, Nguyen, Thai, Oda, Yuko, Tu, Chia-ling
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2016
Matèries:
Physiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4940389/
https://ncbi.nlm.nih.gov/pubmed/27462278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2016.00296
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