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The Involvement of Splicing Factor hnRNP A1 in UVB-Induced Alternative Splicing of hdm2

Human homolog double minute 2 (hdm2), an oncoprotein, which binds to tumor suppressor p53 to facilitate its degradation, has been known to contribute to tumorigenesis. Its splicing variants are reported to be highly expressed in many cancers and can be induced by ultraviolet B light (UVB). However,...

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Veröffentlicht in:Photochem Photobiol
Hauptverfasser: Feng, Jianguo, Li, Li, Tong, Lingying, Tang, Liling, Wu, Shiyong
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4940332/
https://ncbi.nlm.nih.gov/pubmed/26757361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/php.12564
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