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Aspirin inhibits glucose-6-phosphate dehydrogenase activity in HCT 116 cells through acetylation: Identification of aspirin-acetylated sites

Glucose-6-phosphate dehydrogenase (G6PD) catalyzes the first reaction in the pentose phosphate pathway, and generates ribose sugars, which are required for nucleic acid synthesis, and nicotinamide adenine dinucleotide phosphate (NADPH), which is important for neutralization of oxidative stress. The...

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Détails bibliographiques
Publié dans:Mol Med Rep
Auteurs principaux: Ai, Guoqiang, Dachineni, Rakesh, Kumar, D. Ramesh, Alfonso, Lloyd F., Marimuthu, Srinivasan, Bhat, G. Jayarama
Format: Artigo
Langue:Inglês
Publié: D.A. Spandidos 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4940102/
https://ncbi.nlm.nih.gov/pubmed/27356773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2016.5449
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