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Ligand-Based Peptide Design and Combinatorial Peptide Libraries to Target G Protein-Coupled Receptors

G protein-coupled receptors (GPCRs) are considered to represent the most promising drug targets; it has been repeatedly said that a large fraction of the currently marketed drugs elicit their actions by binding to GPCRs (with cited numbers varying from 30–50%). Closer scrutiny, however, shows that o...

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Détails bibliographiques
Publié dans:Curr Pharm Des
Auteurs principaux: Gruber, Christian W., Muttenthaler, Markus, Freissmuth, Michael
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4939874/
https://ncbi.nlm.nih.gov/pubmed/20687879
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