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Ligand-Based Peptide Design and Combinatorial Peptide Libraries to Target G Protein-Coupled Receptors

G protein-coupled receptors (GPCRs) are considered to represent the most promising drug targets; it has been repeatedly said that a large fraction of the currently marketed drugs elicit their actions by binding to GPCRs (with cited numbers varying from 30–50%). Closer scrutiny, however, shows that o...

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Detalhes bibliográficos
Publicado no:Curr Pharm Des
Main Authors: Gruber, Christian W., Muttenthaler, Markus, Freissmuth, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4939874/
https://ncbi.nlm.nih.gov/pubmed/20687879
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