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Developmental Programming: Prenatal Testosterone Excess and Insulin Signaling Disruptions in Female Sheep
Women with polycystic ovary syndrome often manifest insulin resistance. Using a sheep model of polycystic ovary syndrome-like phenotype, we explored the contribution of androgen and insulin in programming and maintaining disruptions in insulin signaling in metabolic tissues. Phosphorylation of AKT,...
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| Publicado en: | Biol Reprod |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Society for the Study of Reproduction, Inc.
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4939741/ https://ncbi.nlm.nih.gov/pubmed/27053365 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.115.136283 |
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