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BLT(1) signalling protects the liver against acetaminophen hepatotoxicity by preventing excessive accumulation of hepatic neutrophils
Leukotriene B(4) (LTB(4)) is a potent chemoattractant for neutrophils. Signalling of LTB(4) receptor type 1 (BLT(1)) has pro-inflammatory functions through neutrophil recruitment. In this study, we investigated whether BLT(1) signalling plays a role in acetaminophen (APAP)-induced liver injury by af...
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| Izdano u: | Sci Rep |
|---|---|
| Glavni autori: | , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4939602/ https://ncbi.nlm.nih.gov/pubmed/27404729 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29650 |
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