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The leukotriene B(4) receptor BLT1 is stabilized by transmembrane helix capping mutations

In this study, we introduced structure-based rational mutations in the guinea pig leukotriene B(4) receptor (gpBLT1) in order to enhance the stabilization of the protein. Elements thought to be unfavorable for the stability of gpBLT1 were extracted based on the stabilization elements established in...

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書目詳細資料
發表在:Biochem Biophys Rep
Main Authors: Hori, Tetsuya, Nakamura, Motonao, Yokomizo, Takehiko, Shimizu, Takao, Miyano, Masashi
格式: Artigo
語言:Inglês
出版: Elsevier 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5668910/
https://ncbi.nlm.nih.gov/pubmed/29124210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2015.09.007
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