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The biofilm inhibitor Carolacton inhibits planktonic growth of virulent pneumococci via a conserved target

New antibacterial compounds, preferentially exploiting novel cellular targets, are urgently needed to fight the increasing resistance of pathogens against conventional antibiotics. Here we demonstrate that Carolacton, a myxobacterial secondary metabolite previously shown to damage Streptococcus muta...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Donner, Jannik, Reck, Michael, Bergmann, Simone, Kirschning, Andreas, Müller, Rolf, Wagner-Döbler, Irene
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4939601/
https://ncbi.nlm.nih.gov/pubmed/27404808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29677
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