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Mechanism for insulin-like peptide 5 distinguishing the homologous relaxin family peptide receptor 3 and 4
The relaxin family peptides play a variety of biological functions by activating four G protein-coupled receptors, RXFP1–4. Among them, insulin-like peptide 5 (INSL5) and relaxin-3 share the highest sequence homology, but they have distinct receptor preference: INSL5 can activate RXFP4 only, while r...
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| Опубликовано в: : | Sci Rep |
|---|---|
| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4939597/ https://ncbi.nlm.nih.gov/pubmed/27404393 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29648 |
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