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Thioesterase Domain Swapping of a Linear Polyketide Tautomycetin with a Macrocyclic Polyketide Pikromycin in Streptomyces sp. CK4412
Tautomycetin (TMC) is a linear polyketide metabolite produced by Streptomyces sp. CK4412 that has been reported to possess multiple biological functions including T cell-specific immunosuppressive and anticancer activities that occur through a mechanism of differential inhibition of protein phosphat...
Kaydedildi:
Yayımlandı: | J Ind Microbiol Biotechnol |
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Asıl Yazarlar: | , , , |
Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
2016
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4939285/ https://ncbi.nlm.nih.gov/pubmed/27277081 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10295-016-1790-2 |
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