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Thioesterase Domain Swapping of a Linear Polyketide Tautomycetin with a Macrocyclic Polyketide Pikromycin in Streptomyces sp. CK4412

Tautomycetin (TMC) is a linear polyketide metabolite produced by Streptomyces sp. CK4412 that has been reported to possess multiple biological functions including T cell-specific immunosuppressive and anticancer activities that occur through a mechanism of differential inhibition of protein phosphat...

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Detaylı Bibliyografya
Yayımlandı:J Ind Microbiol Biotechnol
Asıl Yazarlar: Tripathi, Ashootosh, Choi, Si-Sun, Sherman, David H., Kim, Eung-Soo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4939285/
https://ncbi.nlm.nih.gov/pubmed/27277081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10295-016-1790-2
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