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Expression of an Activated Integrin Promotes Long-Distance Sensory Axon Regeneration in the Spinal Cord
After CNS injury, axon regeneration is blocked by an inhibitory environment consisting of the highly upregulated tenascin-C and chondroitin sulfate proteoglycans (CSPGs). Tenascin-C promotes growth of axons if they express a tenascin-binding integrin, particularly α9β1. Additionally, integrins can b...
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| Udgivet i: | J Neurosci |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Society for Neuroscience
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4938867/ https://ncbi.nlm.nih.gov/pubmed/27383601 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0901-16.2016 |
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