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Expression of an Activated Integrin Promotes Long-Distance Sensory Axon Regeneration in the Spinal Cord

After CNS injury, axon regeneration is blocked by an inhibitory environment consisting of the highly upregulated tenascin-C and chondroitin sulfate proteoglycans (CSPGs). Tenascin-C promotes growth of axons if they express a tenascin-binding integrin, particularly α9β1. Additionally, integrins can b...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Cheah, Menghon, Andrews, Melissa R., Chew, Daniel J., Moloney, Elizabeth B., Verhaagen, Joost, Fässler, Reinhard, Fawcett, James W.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938867/
https://ncbi.nlm.nih.gov/pubmed/27383601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0901-16.2016
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