Chronic Cognitive Dysfunction after Traumatic Brain Injury Is Improved with a Phosphodiesterase 4B Inhibitor

Learning and memory impairments are common in traumatic brain injury (TBI) survivors. However, there are no effective treatments to improve TBI-induced learning and memory impairments. TBI results in decreased cAMP signaling and reduced cAMP-response-element binding protein (CREB) activation, a crit...

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Publicado no:J Neurosci
Main Authors: Titus, David J., Wilson, Nicole M., Freund, Julie E., Carballosa, Melissa M., Sikah, Kevin E., Furones, Concepcion, Dietrich, W. Dalton, Gurney, Mark E., Atkins, Coleen M.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2016
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938858/
https://ncbi.nlm.nih.gov/pubmed/27383587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3212-15.2016
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