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Mast Cell Inhibition Attenuates Cardiac Remodeling and Diastolic Dysfunction in Middle-aged, Ovariectomized Fischer344×Brown Norway Rats

The incidence of left ventricular diastolic dysfunction (LVDD) increases in women following menopause, yet the mechanisms are unclear. Because mast cells participate in the pathological processes of various cardiac diseases, we hypothesized that mast cell inhibition would protect against estrogen lo...

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Pubblicato in:J Cardiovasc Pharmacol
Autori principali: Wang, Hao, da Silva, Jaqueline, Alencar, Allan, Zapata-Sudo, Gisele, Lin, Marina S., Sun, Xuming, Ahmad, Sarfaraz, Ferrario, Carlos M., Groban, Leanne
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938736/
https://ncbi.nlm.nih.gov/pubmed/26981683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0000000000000385
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