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Differential effects of late-life initiation of low-dose enalapril and losartan on diastolic function in senescent Fischer 344 × Brown Norway male rats

No proven pharmacological therapies to delay or reverse age-related diastolic dysfunction exist. We hypothesized that late-life low-dose (non-blood-pressure-lowering) angiotensin-converting enzyme inhibition vs. angiotensin II receptor blockade would be equally efficacious at mitigating diastolic dy...

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Detalhes bibliográficos
Main Authors: Groban, Leanne, Lindsey, Sarah, Wang, Hao, Lin, Marina S., Kassik, Kimberly A., Machado, Frederico S. M., Carter, Christy S.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682061/
https://ncbi.nlm.nih.gov/pubmed/21720770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-011-9283-8
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