CTLA4 blockade reduces immature myeloid cells in head and neck squamous cell carcinoma

Immature myeloid cells such as myeloid-derived suppressor cells (MDSCs) and M2 macrophages play a vital role in the tumor immune escape and tumor progression. Cytotoxic T lymphocyte-associated antigen 4 (CTLA4), as a negative immune checkpoint, is highly expressed in numerous solid tumors. However,...

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Detalles Bibliográficos
Publicado en:Oncoimmunology
Autores principales: Yu, Guang-Tao, Bu, Lin-Lin, Zhao, Yu-Yue, Mao, Liang, Deng, Wei-Wei, Wu, Tian-Fu, Zhang, Wen-Feng, Sun, Zhi-Jun
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2016
Materias:
Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938362/
https://ncbi.nlm.nih.gov/pubmed/27471622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1151594
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