Tumor relapse prevented by combining adoptive T cell therapy with Salmonella typhimurium

We recently reported that therapeutic vaccination with live tumor antigen-producing Salmonella typhimurium rescues dysfunctional endogenous T cell responses and eradicates long-established tumors refractory to αCTLA-4 and αPD-L1 checkpoint inhibitor blockade. Here, we show that live intravenously in...

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Publicat a:Oncoimmunology
Autors principals: Binder, David C., Arina, Ainhoa, Wen, Frank, Tu, Tony, Zhao, Ming, Hoffman, Robert M., Wainwright, Derek A., Schreiber, Hans
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2016
Matèries:
Brief Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938310/
https://ncbi.nlm.nih.gov/pubmed/27471609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1130207
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